{"id":379,"date":"2018-01-30T16:22:16","date_gmt":"2018-01-30T21:22:16","guid":{"rendered":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png"},"modified":"2022-02-07T15:11:57","modified_gmt":"2022-02-07T20:11:57","slug":"screen-shot-2018-01-30-at-4-21-49-pm","status":"inherit","type":"attachment","link":"https:\/\/www.lifetein.com\/blog\/how-hiv-1-integrase-contributes-to-virion-morphogenesis\/screen-shot-2018-01-30-at-4-21-49-pm\/","title":{"rendered":"HIV-1-integrase-binds-viral-RNA-in-virions"},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_crdt_document":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"class_list":["post-379","attachment","type-attachment","status-inherit","hentry"],"aioseo_notices":[],"filename":"Screen-Shot-2018-01-30-at-4.21.49-PM.png","filesize":269386,"description":{"rendered":"<p class=\"attachment\"><a href='https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png'><img decoding=\"async\" width=\"300\" height=\"271\" src=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-300x271.png\" class=\"attachment-medium size-medium\" alt=\"RNA binding defective mutants of integrase yield noninfectious virions\" srcset=\"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-300x271.png 300w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-332x300.png 332w, https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png 728w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>HIV-1 integrase binding to the viral RNA<br \/>\ngenome is necessary for formation of<br \/>\ninfectious viral particles and can be<br \/>\nimpaired by allosteric integrase<br \/>\ninhibitors.<\/p>\n"},"caption":{"rendered":"<p>Integrase exhibits distinct preference for select RNA<br \/>\nstructural elements <a href=\"https:\/\/www.lifetein.com\/blog\/how-hiv-1-integrase-contributes-to-virion-morphogenesis\/screen-shot-2018-01-30-at-4-21-49-pm\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n"},"alt_text":"RNA binding defective mutants of integrase yield noninfectious virions","media_type":"image","mime_type":"image\/png","media_details":{"width":728,"height":658,"file":"2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png","sizes":{"thumbnail":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM-150x150.png","width":150,"height":150,"filesize":21315,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-150x150.png"},"medium":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM-300x271.png","width":300,"height":271,"filesize":66453,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-300x271.png"},"post-thumbnail":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM-728x288.png","width":728,"height":288,"filesize":157700,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-728x288.png"},"large-feature":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM-728x288.png","width":728,"height":288,"filesize":157700,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-728x288.png"},"small-feature":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM-332x300.png","width":332,"height":300,"filesize":79705,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM-332x300.png"},"full":{"file":"Screen-Shot-2018-01-30-at-4.21.49-PM.png","width":728,"height":658,"mime_type":"image\/png","source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png"}},"image_meta":{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0","keywords":[]},"filesize":269386},"post":377,"source_url":"https:\/\/www.lifetein.com\/blog\/wp-content\/uploads\/2018\/01\/Screen-Shot-2018-01-30-at-4.21.49-PM.png","_links":{"self":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media\/379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/media"}],"about":[{"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/types\/attachment"}],"author":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/comments?post=379"}],"wp:attached-to":[{"embeddable":true,"post_type":"post","id":377,"href":"https:\/\/www.lifetein.com\/blog\/wp-json\/wp\/v2\/posts\/377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}