hot spot | LifeTein Peptide Blog https://www.lifetein.com/blog LifeTein: Custom Peptide Synthesis Service Sun, 17 Nov 2024 03:18:45 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://www.lifetein.com/blog/wp-content/uploads/2023/10/cropped-android-chrome-512x512-1-32x32.png hot spot | LifeTein Peptide Blog https://www.lifetein.com/blog 32 32 Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging https://www.lifetein.com/blog/noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging/?utm_source=rss&utm_medium=rss&utm_campaign=noble-metal-gold-and-silver-nanoparticle-are-conjugated-with-peptides-for-cellular-imaging Thu, 15 Feb 2018 20:56:07 +0000 https://www.lifetein.com/blog/?p=426 Noble metal gold (Au) and silver (Ag) nanoparticles (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP and AuNPs-M3 peptide forms an active SERS hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. … Continue reading →

The post Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging first appeared on LifeTein Peptide Blog.]]> Noble metal gold (Au) and silver (Ag) nanoparticles (NPs) are used to conjugate with M3 peptides. The AuNPs-sGFP and AuNPs-M3 peptide forms an active SERS hot spot through self-assembly and GFP complementation. The nanoparticles self-assemble into surface-enhanced Raman-scattering (SERS) nanoclusters. The nanocluster can be a contrast agent for multimodal SERS and photoacoustic microscopy with single-cell sensitivity.

AuNPs coated with M3 peptides-GFP

AuNPs coated with M3 peptides-GFP

Reference: M3 peptide was purchased from LifeTein.

Cellular imaging by targeted assembly of hot-spot SERS and photoacoustic nanoprobes using split-fluorescent protein scaffolds

https://www.nature.com/articles/s41467-018-03046-w

The post Noble metal gold and silver nanoparticle are conjugated with peptides for cellular imaging first appeared on LifeTein Peptide Blog.]]>