https://www.lifetein.com/blog LifeTein: Custom Peptide Synthesis Service Sun, 17 Nov 2024 03:35:16 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://www.lifetein.com/blog/wp-content/uploads/2023/10/cropped-android-chrome-512x512-1-32x32.png https://www.lifetein.com/blog 32 32 https://www.lifetein.com/blog/id2-peptide-for-inhibition-of-tumour-growth/?utm_source=rss&utm_medium=rss&utm_campaign=id2-peptide-for-inhibition-of-tumour-growth Thu, 14 Jan 2016 16:10:23 +0000 http://www.lifetein.com/blog/?p=298 Biotinylated wild-type and modified (pT27 and T27W) ID2 peptides (amino acids 14–34) were synthesized by LifeTein. ID2 binds to the VHL ubiquitin ligase complex. This ID2 peptide could be used to inhibit tumor growth in patients with glioblastoma. LifeTein’s ID2 … Continue reading →

The post ID2 peptide for inhibition of tumour growth first appeared on LifeTein Peptide Blog.]]> Biotinylated wild-type and modified (pT27 and T27W) ID2 peptides (amino acids 14–34) were synthesized by LifeTein. ID2 binds to the VHL ubiquitin ligase complex. This ID2 peptide could be used to inhibit tumor growth in patients with glioblastoma.

LifeTein’s ID2 Peptides Can Inhibit Tumour Growth

Nature, 529, 172–177 (14 January 2016) doi:10.1038/nature16475, An ID2-dependent mechanism for VHL inactivation in cancer.

The post ID2 peptide for inhibition of tumour growth first appeared on LifeTein Peptide Blog.]]> https://www.lifetein.com/blog/nanoparticles-get-help-from-cell-penetrating-peptides/?utm_source=rss&utm_medium=rss&utm_campaign=nanoparticles-get-help-from-cell-penetrating-peptides Thu, 14 Jan 2016 15:41:38 +0000 http://www.lifetein.com/blog/?p=290 Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L—and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate … Continue reading →

The post Nanoparticles Get Help from Cell-Permeable Peptides first appeared on LifeTein Peptide Blog.]]> Some cell-permeable peptides can carry cargo across the cell membrane even without any covalent links. Biotinylated peptides, including L—and D-TAT peptides made by LifeTein, were used in this study to show that two types of cell surface receptors, heparan sulfate proteoglycans, and Neuropilin-1, play critical roles in the delivery of silver-based nanoparticles into cells by cell-permeable peptides.

Nano Particles & Cell-Permeable Peptides

Science Advances 06 Nov 2015: Vol. 1, no. 10, e1500821 DOI: 10.1126/sciadv.1500821.  Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic CPP peptides.

The post Nanoparticles Get Help from Cell-Permeable Peptides first appeared on LifeTein Peptide Blog.]]>